All Full-Time Teacher Part-Time Teacher Administration Staff Retired Teacher
Shuen-Ei Chen - Distinguished professor
Shuen-Ei Chen Distinguished professor
Full-Time Teacher
Animal Production
(04)22840365#227
(04)22860265
shueneic@dragon.nchu.edu.tw
星期三 17:00~19:00、星期四 17:00~19:00、星期五 17:00~19:00
Nutrition, endocrinology, and physiology in domestic animals, myogenesis and muscle wasting, Carbohydrate/Lipid metabolism
Ph.D., Texas A & M Univ.
期刊論文
  1. Chang L.C*., S.K. Chiang*, S.E. Chen*, M.C. Hung. 2022. Targeting 2-oxoglutarate dehydrogenase for cancer treatment. Am. J. Cancer Res. 22:1436-1455.(SCI)(*; equal contribution).
  2. Zhuang Z.-X., S.-E. Chen, C.-F. Chen, E.-C. Lin, S.-Y. Huang. 2021. Single-nucleotide polymorphisms in genes related to oxidative stress and ion channels in chickens are associated with semen quality and hormonal responses by thermal stress. J. Thermal Biol. 105:103220.(SCI)
  3. Chiang S.K., S.E. Chen*, L.C. Chang*. 2021. The crosstalk between heme oxygenase 1 and oxidative stress. Cells. 10:2401. (SCI)(*; equal contribution)
  4. Chou P.-C., P-C. Lin, S.-W. Wu, C.-K. Wang, T.-K. Chung, R.L. Walzem, L.-S. Lai*, S.-E. Chen*. 2021. Differential modulation of 25-hydroxycholecalciferol on innate immunity of broiler breeder hens. Animals (Basel). 11:1742.(SCI)(*; equal contribution).
  5. Zheng H.-T., Z.-X. Zhuang, C.-J. Chen, H.-Y. Liao, H.-L. Chen, H.-C. Hsueh, C.-F. Chen, S.-E. Chen*, S.-Y. Huang*. 2021. Effects of acute heat stress on protein expression and histone modification in the adrenal gland of male layer-type country chickens. Sci. Rep.11:6499.(SCI)(*; equal contribution).
  6. Tiantong, A, K. Sasiwimonrit, S. Saengwong, W. Inyawilert, A. Chaokaur, S. E. Chen. 2021. Optimization of pulsation rate of the milking system for the mammary gland remodeling during involution in Thai crossbred Holstein cows. Trop. Anim. Sci. J. 44:32-38 (Scopus)
  7. Chou P.C., Y.H. Chen, T.K. Chung, R.L. Walzem, L.S. Lai*, S.E. Chen*. 2020. Supplemental 25-hydroxycholecalciferol allievates inflammation and cardiac fibrosis in hens. Int. J. Mol. Sci. 21, 8379. doi:10.3390/ijms21218379.(SCI)(*; These authors contributed equally to this work).
  8. Huang Y.-F*., L.-C. Chang*., C.-Y. Chen, Y.-H. Chen, R. L. Walzem, S.-E. Chen. 2020. Unrestricted feed intake induces ß-cell death and impairs insulin secretion in broiler breeder hens. Animals (Basel).10, 1969; doi:10.3390/ani10111969.(SCI)(*; These authors contributed equally to this work).
  9. Huang J.T*., L.C. Chang*, C.S. Cheng, J.J. Lin, S.Y Huang, S.E. Chen. 2020. Cytotoxicity produced by silicate nanoplatelets: study of cell death mechanisms. Toxins. 12, 623.(*; These authors contributed equally to this work).
  10. Yeh Y.-L., P.-C. Chou, Y.-H. Chen, L.-S. Lai, T.-K. Chung, R.L. Walzem, S.-Y. Huang*, S.-E. Chen*. 2020. 25-hydroxycholecalciferol improves cardiac function and livability in broiler breeder hens-amelioration of blood pressure and vascular remodeling. Poult. Sci. 99:3363–3373.(SCI)(*These authors contributed equally to this work).
  11. Tiantong A., P. Piamya, C.J. Chang, S.E. Chen. 2020. Effects of Enterococcus faecium (SF68) Supplementation on the innate immune defenses and blood biochemical changes in pre-weaning goat kids. J. Anim. Plant Sci. 30:6. https://doi.org/10.36899/JAPS.2020.5.0126.(SCI)
  12. Zhuang Z.-X., S.-E. Chen, C.-F. Chen, E.-C. Lin, S.-Y. Huang. 2020. Genomic regions and pathways associated with thermotolerance in layer-type strain Taiwan country chickens. J. Thermal Biol. DOI:org/10.1016/j.jtherbio.2019.102486.(SCI)
  13. Chiang S.-K., W.-C. Chang, S.-E. Chen*, L.-C. Chang*. 2019. DOCK1 regulates the metastasis through RRP1B-Claudin-1 pathway in Claudin-low breast cancer cells. Cancers. 11: 1762; doi:10.3390/cancers11111762.(SCI)(*These authors contributed equally to this work)
  14. Lin H.Y., P.C. Chou, Y.H. Chen, T.K. Chung, L.S. Lai, R.L. Walzem, S.Y. Huang*, S.E. Chen*. 2019. Dietary supplementation of 25-hydroxycholecalciferol improves livability in broiler breeder hens-amelioration of cardiac pathogenesis and hepatopathology.  Animals (Basel). 9:770. (SCI)(*These authors contributed equally to this work).
  15. Lin H.Y., T.K. Chung, Y.H. Chen, R.L. Walzem, S.E. Chen. 2019. Dietary supplementation of 25-hydroxycholecalciferol improves livability in broiler breeder hens. Poult. Sci. 98:6108–6116.(SCI)(Citation;1)
  16. Tzou Y.M., Y.T. Chan, S.E. Chen, C.C. Wang, P.N. Chiang, H.Y. Teah, J.T. Hung, J.J. Wu. 2019. Use 3-D tomography to reveal structural modification of bentonite-enriched clay by nonionic surfactants: Application of organo-clay composites to detoxify aflatoxin B1 in chickens. J. Hazard. Mater. 375:312-319.(SCI)
  17. Zhuang Z-X., S.-E. Chen, C.-F. Chen, E.-C. Lin, S,-Y. Huang. 2019. Genome-wide association study on the body temperature changes of a broiler-type strain Taiwan country chickens under acute heat stress. J. Thermal Biol. 82:33-42.(SCI)
  18. Chiang S.K., S.E. Chen, L.C. Chang. 2019. A dual role of heme oxygenase-1 in cancer cells. Int. J. Mol. Sci. 20:39.(SCI).(Citation:79)
  19. Tu W.-L., C.-Y. Cheng, C.-J. Chen, H.-L. Chan, S.-H. W, P.-C. Tang, C.-F. Chen, Y.-P. Lee, S.-E. Chen*, S.-Y. Huang*. 2018. Annotation of differential protein expression in the hypothalami of layer-type Taiwan country chickens in response to acute heat stress. J. Therm. Biol. 77;257-272.(SCI)(*These authors contributed equally to this work)(Citation:1)
  20. Tu W.-L. C.-Y. Cheng, C.-J. Chen, H.-L. Chan, S.-H Wang, P.-C. Tang, C.-F. Chen, H.-H. Chen, Y.-P. Lee, S.-E. Chen*, S.-Y. Huang*. 2018. Proteomic analysis of the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress. Anim. Sci. J. 10;1475-1485.(SCI)(*These authors contributed equally to this work)(Citation:2)
  21. Cheng C.-Y., W.-L. Tu, C.-J. Chen, H.-L. Chan, C.-F. Chen, H.-H. Chen, P.-C. Tang, Y.-P. Lee, S.-E Chen,* S.-Y. Huang*, 2018. Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens. Sci. Rep. 8:1320.(SCI)(These authors contributed equally to this work)(Citation:6)
  22. Chang L.-C., S.-K. Chiang, S.-E. Chen, Y.-L. Yu, R.-H. Chou. 2018. Heme oxygenase-1 mediates BAY induced ferroptosis. Cancer Lett. 416: 124-137.(SCI)(Citation:101)(WOS; Highly Cited Papers)
  23. Cheng C.-Y., W.-L. Tu, C.-J. Chen, H.-L. Chen, C.-F. Chen, H.-H. Chen, P.-C. Tang, Y.-P. Li, S.-E. Chen*, S.-Y. Huang*. 2018. Proteomic analysis of thermal regulation of small yellow follicles in broiler-type Taiwan country chickens. J. Poult. Sci. 55:120-136.(SCI)(selected for the Outstanding Paper Award of the Journal of Poultry Science, 2019, Japan)(*;These authors contributed equally to this work)
  24. Wang M.-J., C.-C. Chen, J.-T. Huang, J.-W. Huang, S.-E Chen. 2017. Evaluation of the toxicity of nano-calcium carbonates and their effects on anti-heat stress in laying hens. J. Chin. Soc. Anim. Sci. 46: 223~234.
  25. Yuan C.W., J.T. Huang, C.C. Chen, P.C. Tang, J.W Huang, J.J. Lin, S.Y. Huang*, S.E. Chen*. 2017. Evaluation of efficacy and toxicity of exfoliated silicate nanoclays as a feed additive for fumonisin detoxification. J. Agri. Food Chem. 65:6564-6571.(SCI)(*; These authors contributed equally to this work).(Citation: 1)
  26. Huang C.W.,  Y.J. Chen, J.T. Yang, C.Y. Chen, K.M. Ajuwon, S.E. Chen, N.W. Su, Y.S. Chen, H.J. Mersmann, S.T. Ding. 2017. Docosahexaenoic acid increases accumulation of of adipocyte triacylglycerol through up-regulating lipogeneic gene expression in pigs. Lipids Health. Dis. 16:33.(Citation:5)
  27. Chen C.Y., H.Y. Lin, Y.W. Chen, K.Y. Ko, Y.J. Liu, Y.H. Chen, R. L. Walzem, S.E. Chen. 2017. Obesity-associated cardiac pathogenesis in broiler breeder hens-pathological adaption of cardiac hypertrophy. Poult. Sci. 96:2428-2437.(SCI)(Citation:4)
  28. Chen C.Y., Y.F. Huang, K.Y. Ko, Y.J. Liu, Y.H. Chen, R. L. Walzem, S.E. Chen. 2017. Obesity-associated cardiac pathogenesis in broiler breeder hens-development of metabolic cardiomyopathy. Poult. Sci. 96:2438-2446. (SCI)(Citation:4)
  29. Liu Z.-C., C.-M. Su, Y.-L. Xie, C.-J. Chang, J.-Y. Chen, S.-W. Wu, Y.-H. Chen, R. L. Walzem, S.-Y. Huang, S.-E. Chen. 2016. Intracellular lipid dysregulation interferes with leukocyte function in the ovaries functions of meat-type hens under unrestricted feed intake. Anim. Reprod. Sci.167:40-50.(SCI) (Citation:3)
  30. Tu W.-L., C,-Y. Cheng, S.-H. Wang, P.-C. Tang, C.-F. Chen, H.-H. Chen, Y.-P. Lee, S.-E Chen*, S.-Y. Huang*. 2016. Profiling of differential gene expression in the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress. Theriogenology. 85:483-494.(*; These authors contributed equally to this work)(SCI)(Citation:14)
  31. Cheng C.-Y., Tu W.-L., Wang S.-H., Tang P.-C., Chen C.-F., H.-H. Chen, Lee Y.-P., S.-E Chen*, S.-Y. Huang,*, 2015. Annotation of differential gene expression in small yellow follicles of a broiler-type strain of Taiwan country chickens in response to acute heat stress. PLoS One. 10:e0143418. (*; These authors contributed equally to this work)(SCI) (Citation:9)
  32. Tiantong A., F.-Y. Chang, P.-C. Lin, W.-B. Liu, S.-E. Chen, C.-J. Chang. 2015. Electrophoretic profiles of the proteinous components of plasmaand mammary secretionof Holstein cows received Entercoccus faecium SF68dry-cow treatment. J. Chin. Soc. Anim. Sci. 44: 320-331
  33. Piamya, P, W.-B. Liu, P.-C. Lin, S.-E. Chen, C.-J. Chang. 2015. Topographic profiles of steroid hormones in spontaneously released term fetal membranes of Holstein cows. J. Chin. Soc. Anim. Sci. 44:294-303
  34. Tiantong A., P. Piamya, S.-E. Chen, W.-B. Liu, F.-Y. Chang, P.-C. Lin, H. Nagahata, C.-J. Chang. 2015. Systemic and local bactericidal potentiality in late lactation Holstein-Friesian cows following a combined antibiotics and Enterococcus faecium SF68 dry-cow treatment. Jpn J. Vet. Res.63:139-150(SCI)(Citation:1)
  35. Piamya P., A. Tiantong, S.-E. Chen, W.-B. Liu, C. Yu, H. Nagahata, C.-J. Chang. 2015. Fingerprinting of gelatinase subtypes for different topographic regions on non-retaining placenta of Holstein cows. Animal. 9:490-499.(SCI)(Citation; 2)
  36. Tiantong A., H.-Y. Peng, S.-E. Chen, P. Piamya, W.-B. Liu, C. Yu, M.-T. Chen, H. Nagahata, C.-J. Chang. 2015. Intramammary infusion of an Enterococcus faecium SF68 preparation promoted the involution of drying off Holstein cows partly via neutrophil-associated matrix metalloproteinase 9. Anim. Sci. J. 86:111-119(SCI)(Citation; 2)
  37. Pan Y.-E., Z.-C. Liu, C.-J. Chang, Y.-F. Huang, J.-Y. Lai, R. L. Walzem, S.-E. Chen. 2014. Feed restriction ameliorates metabolic dysregulation and improves reproductive performance of meat-type country chickens. Anim. Reprod. Sci. 151:229-236.(SCI)(Citation;6)
  38. Liao Y.-J., J.-R. Yang, S.-E. Chen, S.-J. Wu, S.-Y. Huang, J.-J. Lin, L.-R. Chen, and P.-C Tang. 2014. Inhibition of fumonisin B1 cytotoxicity activity by nano silicate platelets. PLoS One. 9:e112290.(SCI)(Citation;5)
  39. Yen S.-Y., J.-K. Tseng, S.-M. Chuang, S.-E. Chen, and J.-C. Ju. 2014. Expression and activation of mitogen-activated protein kinase p38 in porcine oocytes under thermal stress. J. Reprod. Dev.60:388-394.(SCI) (Citation; 3)
  40. Liu Z.-C*., Y.-L. Xie*, C.-J. Chang, C.-M. Su, Y.-H. Chen, S.-Y. Huang, R. L. Walzem, and S.-E. Chen. 2014. Feed intake alters immune cell functions and ovarian infiltration in broiler hens-implications for reproductive performance. Biol. Reprod. 90:134, 1-8.(*; These authors contributed equally to this work)(SCI)(Citation; 6)
  41. Li Y.-Z., C.-S. Cheng, C.-J. Chen, Z.-L. Li, Y.-T. Lin, S.-E. Chen* and S.-Y. Huang,*. 2014. Functional annotation of proteomic data induced by carbon tube exposure in chicken heterophils and macrophages. Intl. J. Mol. Sci.15:8372-8392(*; These authors contributed equally to this work)(SCI)(Citation; 5)
  42. Walzem, R.L. and S.E. Chen. 2014. Obesity induced dysfunctions in female reproduction: lessons from birds and mammals. Adv. Nutr. 5:199-206.(SCI)(Citation; 19)
  43. Peng H.-Y., A. Tiantong, S.-E. Chen, P. Piamya, W.-B. Liu, H.-C. Peh, J..-W Lee, M.-T. Chen, H. Nagahata, and C.-J. Chang*. 2013. Ultrasonicated Enterococcus faecium SF68 enhances neutrophil free radical production and udder innate immunity of drying-off dairy cows. J. Dairy Res. 80:349-359 (SCI)(Citation; 2)
  44. Xie Y.-L., Y.-E. Pan, C.-J. Chang, P.-C. Tang, Y.-F. Huang, R. L. Walzem* and S.-E. Chen*. 2012. Palmitic acid in chicken granulosa cell death-lipotoxic mechanisms mediate reproductive inefficacy of broiler breeder hens. Theriogenology. 78:1917-1928.lly to this work) (SCI)(Citation; 10)
  45. Yu T.C., S.-E. Chen, C.H. Ho, H.C. Peh, W.B. Liu, A. Tiantong,, H. Nagahata, and C.J. Chang*. 2012. Involvement of TNF-α and MAPK pathway in the intramammary MMP-9 release of cow neutrophils via degranulation during acute mammary gland involution. Vet. Immunol. Immunopathol. 147: 161-169.(SCI)(Citation; 10)
  46. Pan Y.-E., Z.-C. Liu, C.-J. Chang, Y.-L. Xie, C.-Y. Chen, C.-F. Chen, R. L. Walzem, and S.-E. Chen*. 2012. Ceramide accumulation and upregulation of proinflammatory interleukin-1β exemplify lipotoxicity to mediate declines of reproductive efficacy of broiler hens. Domest. Anim. Endocrinol. 42: 183-194.(SCI)(Citation; 12)
  47. Yu T.C., C.J. Chang*, C.H. Ho, H.C. Peh, S.E. Chen, W.B. Liu, H.Y. Peng, P. Piamya, M.T. Chen, H. Nagahata. 2011. Modifications of the defense and remodeling functionalities of bovine neutrophils inside the mammary gland of milk stasis cows received a commercial dry-cow treatment. Vet. Immunol. Immunopathol. 144: 210- 219.(SCI)(Citation; 6)
  48. Liu H., A. Niu, S.-E. Chen, and Y.-P. Li*. 2011. β3-integrin mediates satellite cell differentiation in regenerating mouse muscle. FASEB J. 25: 1914-1921.(SCI)(Citation; 30)
  49. Liao Y.-J., Chen S.-E., Huang S.-Y., Tang P.-C. 2011. The impact of nanoparticles on animal physiology. J. Agri. & Fore. 60:171-180.
  50. Liu H§., S.-E. Chen§, B. Jin, J. A. Carson, A. Niu, W. Durham. J.-Y. Lai, and Y. P. Li*. 2010. TIMP3: A physiological regulator of adult myogenesis. J. Cell Sci. 123:2914-2921.(§; These authors contributed equally to this work)(SCI)(Citation; 31)
  51. Ho, C.H., C.J. Chang*, W.B. Liu, H.C. Peh, S.E. Chen, H.Y. Chen, T.H. Ho, M.T. Chen, and H. Nagahata, 2010. In situ generation of milk protein-derived peptides in drying-off cows. J. Dairy Res. 77: 487-497.(SCI)(Citation; 1)
  52. Chiang C.C., C.J. Chang*, H.C. Peh, S.E. Chen, B. Yu, M.T. Chen and H. Nagahata. 2010. Calcium homeostasis and the relation to superoxide production in blood and milk neutrophils of lactating goats. Vet. Immunol. Immunopathol. 133: 125-132 (SCI)(Citation; 2)
  53. Chou W.K., T.C. Yu, S.E. Chen, H.C. Peh, W.B. Liu, M.T. Chen, H. Nagahata and C.J. Chang*. 2009. TNFa-mediated plasminogen activation on neutrophils is involved in the high plasmin activity in mammary secretion of drying-off cows. J. Dairy Res. 76: 459-468 (SCI)(Citation;6)
  54. Weng M.H., T.C. Yu, S.E. Chen, H.C. Peh, W.B. Liu, M.T. Chen, H. Nagahata, and C.J. Chang*. 2008. Regional accretion of gelatinase B in mammary gland during gradual and acute involution of dairy animals. J. Dairy Res. 75: 202-210. (SCI)(Citation; 8)
  55. Chen S.-E., B. Jin and Y.-P. Li, 2007. TNF-a regulates myogenesis and muscle regeneration by activating p38 MAPK. Am. J. Physiol.-Cell Physiol. 292. C1660- C1671. (SCI)(Citation; 153)
  56. Chen W.Y., M. H. Weng, S.E. Chen, H.C. Peh, W.B. Liu, T.C. Yu, M.C. Huang, M.T. Chen, H. Nagahata and C.J. Chang*. 2007. Profile of gelatinase capacity of raw goat milk and the implication to milk quality. J. Dairy Sci. 90: 4954-4965. (SCI)(Citation; 8)
  57. Zhan M., B. Jin, S.-E. Chen, J. M. Reecy and Y.-P. Li*, 2007. TACE release of TNF-α mediates mechanotransduction-induced activation of p38 MAPK and myogenesis. J. Cell Sci. 120. 692-701.(SCI)(Citation; 60)
  58. Chen S.E., J.P. McMurtry and R.L. Walzem*. 2006. Overfeeding-induced ovarian dysfunction in broiler breeder hens is associated with lipotoxicity. Poult. Sci. 85. 70-81. (SCI)(Citation; 52)
  59. Chen S.-E., E. Gerken, Y. Zhang, M. Zhan, R.K. Mohan, A.S. Li, M.B. Reid and Y.-P. Li*, 2005. Role of TNF-a signaling in regeneration of cardiotoxin-injured muscle. Am. J. Physiol.-Cell Physiol. 289. C1179-C1187. (SCI)(Citation; 89)
  60. Chen, S.E., K.E. Nestor, R.L. Walzem, V.L. Menuiot, H. Zhu, R.J. Hansen and W.L. Bacon*, 1999. Effect of divergent selection for total plasma phosphorus on plasma and yolk very low density lipoprotein and plasma concentration of selected hormones in laying Japanese quail. Poult. Sci. 78: 1241-1251.(SCI)(Citation; 16)
  61. Ockerman*, H.W. and Chen S.-E., 1996. Actions of some important bacterial enzymes in fermented meats. Meat focus Int’l. 5: 359-362.
 
專利技術
  1. Chen Shuen Ei, Chung Thau Kiong, Daniel Raederstorff, Wolfgang Schalch. Combination of Hydroxyvitamin D and Antioxidants/Anti-inflammatories for Human Nutraceuticals. International publication number; WO 2016/113387 A1. US Patent #11040045, duration from 2021/06/22-2036/01/15.
  2. Chen Shuen Ei, Chung Thau Kiong, Daniel Raederstorff, Wolfgang Schalch. Combination of Hydroxyvitamin D and Antioxidants/Anti-inflammatories for Human Nutraceuticals. International publication number; WO 2016/113387 A1. US Patent #10668008, duration from 2020/06/02-2036/06/15.
  3. Chen Shuen Ei, Chung Thau Kiong, Celi Pietro. Combination of Hydroxyvitamin D and Antioxidants/Anti-inflammatories for Bovine Health. International publication number; WO 2016/113389 A1. US Patent #10517316, Japan Patent #6623418, duration from 2019/12/06-2036/01/15.
  4. Chen Shuen Ei, Chung Thau Kiong. Combination of Hydroxyvitamin D and Antioxidants/Anti-inflammatories for Poultry Ovarian Health. International publication number; WO 2016/113382 A1. Japan Patent #6623417, duration from 2019/12/06-2036/01/15.
  5. Chen Shuen Ei, Chung Thau Kiong. Poultry Feed with Combination of Hydroxyvitamin D and Antioxidants/Anti-inflammatories. International publication number; WO 2016/113384 A1. Japan Patent #6623415, duration from 2019/12/06-2036/01/15.
  6. Chen Shuen Ei, Chung Thau Kiong. Method of Preventing Obesity and Cardiovascular Problems in Poultry. International publication number; WO 2016/113383 A1. US Patent #10863756. Japan Patent #6623416, duration from 2019/12/06- 2036/01/15.
  7. Chen Shuen-Ei, Chung Thau Kiong, Combination of Hydroxyvitamin D and Anti-inflammatories for Sustained Plasma 17-b Estradiol Levels. International publication number; WO 2016/113385 A1. Japan Patent #6550651,Canada patent # CA 2973431,  Indonesia patent #P000074712, Columbia patent, #21590, duration from 2019/07/12-2036/01/15.
  8. 鄒裕民、詹雅婷、鍾文鑫、陳洵一、黃振文、林耀東、劉雨庭、黃盈潔。2017。微奈米化鈉質膨潤土、其製備方法及其用途 (MICRO-NANO SODIUM BENTONITE, MANUFACTURING METHOD AND USE THEREOF)。中華民國發明專利第I 591159號，專利期限2017, 7/11-2036, 7/14。
  9. 陳洵一、林江珍。2014。使用奈米矽片來抑制黴菌毒素(Inhibition of Mycotoxin with Nano Silicate Platelet)。中華民國發明專利第I 434657號，專利期限2014, 4/21-2032,2/21。
  10.  陳洵一。   2015/9, 微奈米鈣作為飼料添加劑的安全評估平台，新台幣30萬元/台茂奈米生化股份有限公司